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Spasticity & Marijuana

Spasticity is painful muscle spasms and stiffness. There are many diseases and disorders that result in spasticity, such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), cerebral palsy, and injuries to the spinal cord. The endocannabinoid system helps to regulate nerve transmission. It is thought that the cannabinoids in cannabis can regulate the damaged nerve conduction system. These cannabinoids are also able to limit the progression of these diseases over time by limiting the excessive glutamate release and reducing the neural damage. In a recent study at the University of California Center for Medicinal Cannabis Research, patients who were already on other medication for MS, were given THC cannabis or a placebo to smoke. The results showed that there was a significant reduction in spasticity in the cannabis group, as well as a pain reduction among 50% of the patients. Sublingual cannabis has been found as more affective than ingestion. There was also objective improvement in smoking cannabis, as shown by the California Center study.

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