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Arthritis & Marijuana

Arthritis is an inflammation of the joint space that causes stiffness, pain, and potentially loss of movement or deformation. Synovial membranes in the joints have a robust endocannabinoid system. CB1 and CB2 are the primary cannabinoid receptors in the body. CB2 is found primarily on the immune cells. Activation of these cells by medical marijuana is thought to decrease inflammation. When marijuana with a higher CBD concentration is used in patients with arthritis, it seems the powerful anti-inflammatory effects of cannabis can control the secretions of pro-inflammatory factors resulting in less damage to the joint. This decreased inflammation results in less joint pain and perhaps decelerates joint damage. There are even indications that, along with the traditional method of using medical marijuana (oral, smoking and vaporizing), topical application could be effective in assisting with arthritis.

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