Hi there! You should inform your treating physician if you would like to use cannabis while taking blood thinners such as Warfarin. Please see these previously answered questions on the matter for more information: https://www.hellomd.com/answers/58eed25a54133c2d0553d64c/are-there-interactions-between-blood-thinners-and-marijuana https://www.hellomd.com/answers/5a5f725fd31dce000697f1be/is-cbd-oil-safe-to-take-if-your-taking-cumadin
Smoking cannabis/ using a vape-pen would cause CBD levels to increase more rapidly in the bloodstream (pulmonary vs gastric/ mucosal absorption) but the interaction with warfarin (assuming cannabinoid levels reaching the same level in the blood) would be the same. Informing your primary care doctor about your use of medical cannabis products is highly advised. I hope this answers your query!