What studies are available to support the negative effects of cannabis on the teenage brain?

Hello, great question. Here are a few to get you started:

  1. J.M. Bostwick, "Blurred Boundaries: The Therapeutics and Politics of Medical Marijuana," Mayo Clinic Proceedings 87, no 2 (2012):172-86. This study showed that the effects of cannabis on the developing brain are greater than a mature brain, partly because cannabis can interfere with the development of the endocannabinoid system, which is necessary for homeostasis.
  2. Avshalom Caspia, Terrie E. Moffitt, Mary Cannon et al., "Moderation of the Effect of Adolescent-Onset Cannabis Use on Adult Psychosis…" Biological Psychiatry 57, no 10 (2005):1117-27. This study showed that some adolescents can be more vulnerable to developing schizophrenia if they carry a specific gene variation in their DNA.
  3. J. Jacobus, S. Bava, M. Cohen-Zion, et al., "Functional Consequences of Marijuana Use in Adolescents," Pharmacology Biochemistry, and Behavior 92, no 4 (2009): 559-65. This study showed that heavy use of cannabis can result in deficits in memory and attention, as well as mood problems, which can negatively impact their school work. It is noted that the abnormalities can disappear after 3 months of cannabis abstinence.


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