"The pup will be in the plane with me and loves to say hi to everyone and I need to have her calm She weighs about 14 pounds."
You could always try a small dose of a CBD dog treat – CBD has many of the same effects on pets as it does humans. You might consider something like these CBD Dog Treats from Holistic Hound: https://www.hellomd.com/products/5b57a30002f1740001522f46/cbd-dog-treats-75-mg
Kevin makes a great suggestion.
Although not about anxiety, a 2018 study peformed by researchers from the College of Veterinary Medicine, Cornell University concluded that
2mg CBD/kg, twice daily can help increase comfort and activity in dogs with osteoarthritis—
That works out to about:
1mg of CBD per every pound, twice daily.
Since your companion is 14lbs, I recommend that you give your canine companion one (7.5mg CBD) or two (15mg CBD) treats one hour before departure.
I hope this helps!