There are no established guidelines regarding the matter. However, if vaping the oil and undergoing general anesthesia, in order to reduce the chance of respiratory complications during and after sugery, I recommend that you discontinue vaping for at least one week prior to surgery. Also, very high doses of CBD can possibly reduce the body’s ability to form blood clots. Your anesthesiologist will/should make sure that ability is not compromised. Furthermore, CBD can lower blood pressure, which can also make things a bit trickier for your anesthesiologist. Regardless, you should fully disclose the matter to your surgeon and anesthesiologist. Also, in order to evaluate your specific case properly, I advise that you consult with a physician. This information should not be taken as medical advice.