"I want to treat my life-long anxiety and depression with hemp-derived CBD oil but I know that statins such as atorvastatin don’t play well with CBD. My primary doc won’t work with me on CBD. Would I be safe in just cutting my 20mg of atorvastatin in half? I have seen a D.O. who will work with me but I would rather not change doctors. Thanks very much!"
Hello. CBD may increase serum concentrations of some statins (atorvastatin and simvastatin, but not pravastatin or rosuvastatin). It is unfortunate that your primary care physician will not treat you if you are on CBD. However, I would not recommend you cutting your medication in half. It is important to leave that up to your physician as they are trained to interpret and monitor your blood cholesterol levels in conjunction with prescribing the appropriate dosages of medications. I would prefer you change doctors, or find a provider that will monitor your cholesterol while taking CBD. Overall, Cannabis is generally well-tolerated, and serious adverse effects are rare.