The 7 Best Medical Marijuana Strains in Ohio

There are over 700 strains of cannabis, colorfully named and divided by their Indica, Sativa, or Hybrid subspecies. Cannabis farmers often cross-breed to create new strains that enhance specific characteristics like Tetrahydrocannabinol (THC) content or the terpene profile.

Medical marijuana flower is legal within the state of Ohio; however
growing marijuana for personal or family use is not legal in Ohio. And while cannabis flower is available to purchase at legal dispensaries, smoking it is not permitted.

How to Choose a Medical Marijuana Strain


It can be overwhelming to choose a marijuana strain. One fast way to narrow down your choices is to decide whether an Indica, Sativa, or Hybrid strain suits your needs. Simply put, Sativas have uplifting, energizing, and heady effects. They are best consumed in the daytime to treat depression and chronic pain.

Indica strains have relaxing, pain-relieving, sedative effects felt in the body. They effectively treat insomnia, pain, and nausea. Hybrids have varying combinations of Indica and Sativa effects. In reality, there are exceptions to the Indica and Sativa labels, so it’s always a good idea to ask the dispensary staff for recommendations.

Budtenders help clients in a dispensary to select marijuana

Many patients choose a strain based on Tetrahydrocannabinol (THC) level, but this is only one compound in cannabis that plays a role. High THC levels may cause anxiety, and Cannabidiol (CBD) helps balance out anxious feelings.

Terpenes are another vital factor as they give plants their scent and flavor and have additional benefits. It’s possible that the best way to choose a strain is to follow your nose by selecting a strain that smells the best to you. Often what smells good to you contains what your body needs.

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What to Know About Medical Marijuana in Ohio

Cannabis is legal for medical consumption in Ohio, which means patients must have a doctor qualify their medical condition to register for a medical marijuana card. Qualifying conditions include cancer, chronic pain, PTSD, epilepsy, and more. Once you have your medical card, you can visit many legal marijuana dispensaries that carry a variety of cannabis strains and products like oils, tinctures, edibles, lotions, and flower. But smoking cannabis is not permitted in Ohio, so flower must be vaped in a vaporizer.

The 7 Best Medical Marijuana Strains in Ohio

Here is our list of the top seven strains of medical cannabis available in Ohio, including Indica, Sativa, and Hybrid strains.

Willie’s Reserve Larry Cake

Willie's Reserve cannabis flower

Patients in Ohio can buy Willie’s Reserve Larry Cake strain at Buckeye Botanicals. This Indica strain, also known as Ice Cream Cake, offers a relaxing full-body high with a sweet and floral flavor. The flavor profiles will be more prominent since you’ll be vaping your weed. This strain has caryophyllene, myrcene,and limonene terpenes.

Curaleaf White Hot Guava

Curaleaf White Hot Guava

You can buy Curaleaf White Hot Guava at Herbology in Newark, Ohio. This Indica strain feels euphoric and calming. The flavor is funky and gassy with sweet notes of grape and guava. There are trace amounts of CBD that add to anxiety relief.

Locally Grown D Star


Locally Grown’s D Star strain is available at Pure Ohio Wellness. It’s an Indica-dominant Hybrid cross of Sensi Star and Sour Diesel that creates a relaxing and euphoric body high. It’s also high in THC (28%), which means it’s perfect for treating pain and insomnia.

Standard Wellness Animal Fire OG


You can find the Standard Wellness Animal OG strain at Terasana. This Hybrid of Girl Scout Cookies and Fire OG may help increase appetite and ease symptoms of chronic pain, depression, and insomnia. The top four terpenes include caryophyllene, limonene, linalool, and humulene.

Cresco Mac #7


Patients in Ohio can purchase Cresco Mac #7 at Sunnyside. Mac #7 is a Sativa-leaning Hybrid strain, and its uplifting and euphoric effects last throughout the day. Energizing and calming, this strain’s orange and floral flavor comes from caryophyllene, linalool, and limonene terpenes—an excellent strain for daytime pain, depression, and stress relief.

Buckeye Relief Grapefruit Sour Dream

Buckeye Relief Grapefruit Sour Dream

Buckeye Relief’s Grapefruit Sour Dream is available to buy at RISE Cannabis. It’s a Sativa strain perfect for beginners looking for a euphoric and silly high that doesn’t feel too stoney. A cross of Cookies and Cream, Blue Dream, and Grapefruit Diesel. The flavor is sour with sweet berry and gas.

Ancient Roots Sweet Rylando

Ancient Roots Sweet Rylando

You can buy Ancient Roots Sweet Rylando strain at Bloom Medicinals. This Sativa strain is energizing and relaxing, like an all-day coffee to motivate you to clean and exercise. It smells like fresh grass and gas and it can be used to treat pain relief and increase appetite.

Get Your Medical Document & Purchase Medical Marijuana

It’s easy to get your medical document with the online Telehealth service HelloMD. Register, pay, and receive an online medical consultation with a licensed partitioner and purchase medical cannabis today. You only pay if you’re approved.


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