Not to my knowledge. I have spoken with many people about cannabis and how it helps with the urinary symptoms associated with prostate cancer, interstitial cystitis, prostate hypertrophy, and other symptoms. It seems to help relax bladder and other micturition muscules and many people report that they have less of an issue with urgency and frequency of urination. Often times people who were awakening mutliple times per night to urinate are now able to sleep through the night with many fewer sleep interruptions. It also helps women with these same issues.